论文部分内容阅读
目的:研究非甾体抗炎药(NSAIDs)致上消化道出血的临床特点。方法:回顾性分析72例NSAIDs与196例溃疡及胃黏膜病变致上消化道出血临床资料,比较两组基本情况。结果:NSAIDs组服药后2周内发病占63.9%(46/72),且年龄偏大、多有心脑血管病史、出血前临床症状不明显;两组性别、溃疡病史、治疗及预后差异无统计学意义(P>0.05)。结论:NSAIDs致上消化道出血起病隐匿,应加强防治。
Objective: To study the clinical features of non-steroidal anti-inflammatory drugs (NSAIDs) induced upper gastrointestinal bleeding. Methods: A retrospective analysis of 72 cases of NSAIDs and 196 cases of gastric ulcer and gastric mucosal lesions caused by upper gastrointestinal bleeding clinical data were compared between the two groups. Results: The incidences of NSAIDs were 63.9% (46/72) within 2 weeks after taking the medicine, and were older and had more history of cardiovascular and cerebrovascular diseases. The clinical symptoms before the bleeding were not obvious. There was no significant difference in gender, history of ulcer, treatment and prognosis between the two groups. Statistical significance (P> 0.05). Conclusion: NSAIDs cause insidious upper gastrointestinal bleeding, and should be strengthened prevention and treatment.