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目的:分析腹腔化疗对晚期腹腔恶性肿瘤的治疗效果。方法:采用腹腔穿刺给药。有腹水者,抽 尽腹水后,将 5-Fu 1000 mg+卡铂 200- 300 mg,分别加生理盐水40ml注入腹腔;若无腹水,将 5-Fu、卡铂+2000ml生理盐水作腹腔灌注。结果:32例患者中,胃癌20例,肠癌12例,合并腹水者18例。结果显效10例,有效 5例,稳定 2例,无效 1例,有效率 83.3%。可评估的恶性肿瘤 32例中,CR 2例,PR 10例,SD 13例,PD 7例,有效率(CR+PR)37.5%。结论:该疗法对老年晚期腹腔内肿瘤病人,能起到改善症状,缓解病情,延长生存期的作用。并且操作简单,费用较低。
Objective: To analyze the effect of intraperitoneal chemotherapy on advanced abdominal malignant tumors. Methods: The use of abdominal puncture administration. With ascites, after aspirating ascites, 5-fu 1000 mg + carboplatin 200 - 300 mg, respectively, plus normal saline 40ml into the abdominal cavity; if no ascites, 5-Fu, carboplatin + 2000ml saline for intraperitoneal perfusion. Results: Of the 32 patients, 20 were gastric cancer, 12 were intestinal cancer, and 18 had ascites. The results were markedly effective in 10 cases, effective in 5 cases, stable in 2 cases, invalid in 1 case, and the effective rate was 83.3%. Of the 32 malignant tumors that could be evaluated, 2 were CR, 10 were PR, 13 were SD, and 7 were PD. The effective rate (CR+PR) was 37.5%. Conclusion: This therapy can improve the symptoms of the elderly patients with advanced intra-abdominal tumors, relieve the disease, and prolong the survival period. And the operation is simple and the cost is low.