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对29例脑梗塞患者和59例正常人进行性格评定,且测定了23例男性脑梗塞患者的血清性激素:睾酮(T)、雌二醇(E2)和血脂:总胆固醇(TC)、甘油三酯(TG),及56例男性正常对照者的血清性激素(T、E2)。结果发现:(1)脑梗塞组A型性格所占百分率明显高于对照组(P<0.001);(2)男性脑梗塞患者尤其是A型性格患者存在性激素失衡,即血清T水平降低(P<0.05)、E2/T比值增高(P<0.05);(3)脑梗塞组中A型性格患者的血清TC、TG高于B型性格(但P>0.05)。结论:A型性格对脑梗塞的影响至少有一部分是通过影响血清性激素(T、E2)及血脂而发生的。
Twenty-nine patients with cerebral infarction and 59 normal subjects were evaluated for their personality and serum levels of testosterone (T), estradiol (E2), and total cholesterol (TC) were measured in 23 male patients with cerebral infarction. Ester (TG), and 56 male normal controls were tested for serum sex hormones (T, E2). The results showed that: (1) The percentage of type A personality in cerebral infarction group was significantly higher than that in control group (P <0.001); (2) Sex hormone imbalance was found in male patients with cerebral infarction, especially in type A personality, (P <0.05), and the ratio of E2 / T increased (P <0.05). (3) The level of TC and TG in patients with type A personality in cerebral infarction group were higher than those in type B (P0.05) . CONCLUSIONS: Type A personality affects at least part of cerebral infarction by affecting serum sex hormones (T, E2) and blood lipids.