抗磷脂质抗体主要是与带有阳性电荷的磷脂发生反应的免疫球蛋白,近来因与全身以及神经系统疾病有关而引起重视。这种抗体多见于系统性红斑性狼疮(SLE),提示与免疫机制引起的血栓形成病理相关。近来发现不仅与血栓形成有关,还与许多神经系统疾病的病情密切相关。虽然SLE往往合并神经症状,但其表现却是多种多样,无持异性。尽管这些症状的发病机制有多种学说,已证明狼疮抗凝因 Antiphospholipid antibodies are mainly immunoglobulins that react with positively charged phospholipids and have recently attracted attention due to their systemic and neurological disorders. This antibody is more common in systemic lupus erythematosus (SLE), suggesting that the pathogenesis of thrombosis caused by the immune mechanism. Recently it has been found that it is not only related to thrombosis, but also closely related to the condition of many nervous system diseases. Although SLE tends to have neurological symptoms, its performance is varied and non-heterosexual. Although there are multiple theories on the pathogenesis of these symptoms, lupus has been shown to be anticoagulant