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将“紫金锭”改剂为“紫金胶囊”,运用该药对大鼠细菌性前列腺炎症模型进行病理形态学改变观察发 现:该药能抑制炎症所致腺体重量增加,也能抑制细菌性前列腺炎所致的纤维组织增生,与男康片组比较差异 有显著性意义(P<0.05)。紫金锭胶囊对腹腔注射醋酸所致小鼠扭体反应及腹腔毛细血管通透性增高实验证 实,该药能明显减少小鼠扭体次数及降低腹腔毛细血管通透性,优于阳性对照组(P<0.01),实验研究表明,紫 金胶囊具有消炎、镇痛、抑菌等作用,是治疗慢性前列腺炎的一种有效药物。
The “Xijin Ingot” was modified to be “Zijin Capsule”. The use of this medicine to observe the pathomorphological changes of the bacterial prostatic inflammation model in rats revealed that the drug can inhibit the increase in the weight of glands caused by inflammation, and also inhibit the bacterial prostate. The fibrous tissue proliferation caused by inflammation was significantly different from that of the male Kang Tablet group (P<0.05). The effect of Zijinding Capsule on writhing in mice and increase in capillary permeability of abdominal cavity induced by intraperitoneal injection of acetic acid was confirmed. The drug can significantly reduce the number of writhing and decrease the permeability of the capillary in the abdominal cavity, and is superior to the positive control group ( P<0.01), experimental studies have shown that Zijin capsule has anti-inflammatory, analgesic, and antibacterial effects and is an effective drug for the treatment of chronic prostatitis.