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目的探讨动态心电图和动态血压应用于监测原发性高血压病患者的临床效果,为原发性高血压病的临床诊治提供借鉴和参考。方法选取2010年12月—2015年1月收治的原发性高血压病患者78例作为研究对象,根据患者是否合并心力衰竭(心衰)分为心衰组55例和无心衰组57例,对两组患者的动态心电图和动态血压情况进行观察和比较。计量资料采用t检验,P<0.05为差异有统计学意义。结果无心衰组患者的SBP水平为(159.45±14.33)mm Hg(1 mm Hg=0.133 kPa),显著低于心衰组的(178.45±9.45)mm Hg,差异有统计学意义(P<0.05)。无心衰组患者的R波振幅综合(∑R)、QTC和V1导联P波终末电势(P wave terminal force of V1,PTF-V1)水平分别为(124.35±18.34)mV(0.412±0.011)s、(0.023±0.015)mm·s,均显著低于心衰组的(132.87±8.93)mV(0.435±0.022)s、(0.055±0.016)、、mm·s,差异均有统计学意义(均P<0.05)。结论动态心电图和动态血压监测可用于判断原发性高血压病患者的病情,对患者合并心衰情况进行鉴别,为患者的临床诊治提供参考借鉴。
Objective To investigate the clinical effects of ambulatory ECG and ambulatory blood pressure monitoring in patients with essential hypertension and provide references for the clinical diagnosis and treatment of essential hypertension. Methods Seventy-eight patients with essential hypertension admitted from December 2010 to January 2015 were enrolled in this study. According to whether patients with heart failure (heart failure) were divided into heart failure group (n = 55) and heart failure group (n = 57) , The dynamic electrocardiogram and ambulatory blood pressure of two groups were observed and compared. Measurement data using t test, P <0.05 for the difference was statistically significant. Results The SBP level in patients without heart failure was (159.45 ± 14.33) mm Hg (1 mm Hg = 0.133 kPa), which was significantly lower than that in patients with heart failure (178.45 ± 9.45 mm Hg, P <0.05 ). The levels of R wave amplitude synthesis (ΣR), QTC and V1 wave P wave terminal force of V1 (PTF-V1) in patients without heart failure were (124.35 ± 18.34) mV (0.412 ± 0.011 ) s, (0.023 ± 0.015) mm · s were significantly lower than those in heart failure group (132.87 ± 8.93) mV (0.435 ± 0.022) s and (0.055 ± 0.016) mm · s, respectively (All P <0.05). Conclusions Holter monitoring and ambulatory blood pressure monitoring can be used to judge the condition of patients with essential hypertension and to identify the patients with heart failure, so as to provide reference for the clinical diagnosis and treatment of patients.