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T2DM并冠心病的病例58例,作为Ⅰ组;T2DM不合并冠心病病例42例为Ⅱ组;无糖尿病的冠心病患者60例为Ⅲ组。比较分析患者的一般情况、血糖、血压、血脂、糖化血红蛋白(HbA1C),并计算胰岛素敏感指数(ISI);对Ⅰ组与Ⅲ组患者冠脉造影结果进行对比分析。结果:显示高血压、HbA1C、甘油三脂(TG)、低密度脂蛋白(LDL-C)、ISI与糖尿病患者发生冠心病密切相关;糖尿病合并冠心病患者以3支病变多见。结论:T2DM患者致动脉粥样硬化的因素多而复杂;主要表现为冠状血管广泛、严重的粥样硬化。
58 cases of T2DM and coronary heart disease, as group Ⅰ; 42 cases of T2DM without coronary heart disease in group Ⅱ; 60 cases of non-diabetic patients with coronary heart disease group Ⅲ. The general conditions of patients, blood glucose, blood pressure, blood lipid, HbA1C were calculated and compared. The insulin sensitivity index (ISI) was calculated. The results of coronary angiography were compared between group Ⅰ and group Ⅲ. Results: High blood pressure, HbA1C, triglyceride (TG), low density lipoprotein (LDL-C) and ISI were closely related to coronary heart disease in patients with diabetes mellitus; diabetic patients with coronary heart disease were more common in 3 lesions. Conclusions: The causes of atherosclerosis in T2DM patients are many and complex. The main manifestations are extensive and severe coronary atherosclerosis.