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本文报道了SOD复合酶外用制剂对73例老年瘙痒症患者的疗效。实验采用双盲对照法,按预先制定的方法用药。结果表明,观察组有效率为88％,与对照组比较有非常显著的差异(X~2=44.94,P<0.01)。同时动物实验亦证明SOD复合酶中SOD活性不同(400u/ml,1000u/ml,2500u/ml),对豚鼠离体回肠肌收缩的最大张力的影响不同,分别降低其收缩的最大肌张力14±4.8％,28±6.8％,64±15％,给药前后比较有显著和非常显著的差异(P<0.05和P<0.01)。这提示SOD复合酶外用制剂有类似扑尔敏的抗过
This article reported the efficacy of external preparations of SOD complex enzyme in 73 elderly pruritus patients. The experiment was double-blind and controlled according to a pre-established method. The results showed that the effective rate in the observation group was 88%, and there was a very significant difference compared with the control group (X~2=44.94, P<0.01). At the same time animal experiments also proved that SOD activity in SOD complex enzyme is different (400u/ml, 1000u/ml, 2500u/ml), and the effect on the maximum tension of guinea pig isolated ileum muscle is different, and the maximum muscle tension of contraction is reduced respectively 14± 4.8%, 28±6.8%, 64±15%, there were significant and very significant differences before and after administration (P<0.05 and P<0.01). This suggests that the SOD compound enzyme topical preparation has a similar anti-overactive