论文部分内容阅读
分子靶向治疗(Molecular targeted therapy)是在细胞分子水平上,针对已经明确的致癌位点(该位点可以是肿瘤细胞内部的一个蛋白分子,也可以是一个基因片段)来设计相应的治疗药物,药物进入人体后会特异性地选择致癌位点相结合并发生作用,通过阻断肿瘤细胞或相关细胞的信号传导,来控制细胞基因表达的改变,从而特异性地抑制或杀死肿瘤细胞。据2008年统计,全球每年新发乳腺癌病例高达100
Molecular targeted therapy is the design of the corresponding therapeutic drug at the cellular and molecular level for an already defined oncogenic site (this site can be a protein molecule inside a tumor cell or a gene fragment) , The drug enters the human body to selectively combine and act on the site of carcinogenesis to control the change of the gene expression of the cell by blocking the signal transduction of tumor cells or related cells so as to specifically inhibit or kill the tumor cells. According to statistics in 2008, the number of new breast cancer cases in the world is as high as 100 each year