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作者在用X线照射胸腔以造成小鼠溃疡性食管炎的实验时偶然发现,在下纵隔单次照射250 kV的X线18 Gy后,约45％的小鼠于第9天发生了在形态和性质上酷似人类慢性十二指肠溃疡的病变。而上纵隔同样照射则不引起十二指肠溃疡。作者将这种远隔照射部位发生的溃疡称为异位(abscopal)效应溃疡。方法与结果:107只重15～40g雌性CFLP小鼠,分三个实验组:对照组(C);上纵隔照射组(U),T_4以上;下纵隔照射组(L),T_5～T_(10),照射面积、剂量同U组。在照射后3天f诱导期)和照射后7天(溃疡出现
In an experiment in which the chest was irradiated with X rays to cause ulcerative esophagitis in mice, it was found by chance that about 45% of the mice developed morphological and / Nature resembles human chronic duodenal ulcer lesions. The same irradiation of the mediastinum does not cause duodenal ulcer. The authors describe this ulceration at a distant site as an ulceration of the abscopal effect. Methods and Results: A total of 107 female CFLP mice weighing 15-40 g were divided into three groups: control group (C), upper mediastinum irradiation group (U) and above T_4, lower mediastinum irradiation group (L), T_5 ~ T_ 10), irradiation area, dose with the U group. 3 days after irradiation f induction period) and 7 days after irradiation (ulceration occurred