骨髓增生异常综合征 (ＭＤＳ)系起源于全潜能干细胞水平的恶性克隆性疾病。其病理基础为造血干、祖细胞的分化功能失常 ,导致病态及无效造血。我们对我院 33例ＭＤＳ患者及 33例正常人进行外周血涂片及骨髓涂片与活检的对比研究 ,以探讨二者在骨髓增生异常综合征诊断中的应用。 Myelodysplastic syndromes (MDSs) are malignant clonal diseases that arise from the level of all-potential stem cells. The pathological basis for hematopoietic stem cell progenitor cell dysfunction, resulting in morbidity and ineffective hematopoiesis. We compared 33 cases of MDS patients and 33 normal subjects in our hospital with peripheral blood smears and bone marrow smears and biopsy to explore their application in the diagnosis of myelodysplastic syndromes.