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人类染色体末端或端粒联合是一种罕见的现象,曾在毛细血管扩张性共济失调和Thiberge-Weissenbach综合征病人中,被SV40感染的培养的成纤维细胞和肾细胞以及人类成纤维细胞衰老过程中观察到。在某些病人中也曾发现端粒联合频率较高,本文报告一例正常个体细胞在加阿菲迪霉素培养时端粒联合频率较高。三例正常个体的外周血液样品在加阿菲迪霉素(0.2uM)的RPMI-1640培养基上培养24小时,例1、2和3分别获得用于分析
Human chromosome telomere or telomere association is a rare phenomenon that has been senescent in fibroblast expansion ataxia and patients with Thiberge-Weissenbach syndrome, cultured fibroblasts and renal cells infected with SV40, and human fibroblasts. Observed during the process. In some patients, it has also been found that the frequency of telomere joint is high. This article reports a case of a normal individual cell in the afi domycin culture when the telomere joint frequency is higher. Peripheral blood samples of three normal individuals were cultured on affiomycin (0.2 uM) in RPMI-1640 medium for 24 hours. Examples 1, 2 and 3 were obtained for analysis.