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目前对青光眼的治疗方法主要是通过药物或手术降低眼压 ,然而单纯降低眼压并不足以防止青光眼引起的视神经进行性损害 ,其他病理机制也很可能导致视网膜神经节细胞(retinalganglioncell,RGC)和视神经的损伤。所有可能造成RGC凋亡的因素如谷氨酸毒性、营养因子中断、血管异常、?
At present, the treatment of glaucoma mainly reduces the intraocular pressure by drugs or surgery. However, simply lowering the intraocular pressure is not enough to prevent the progressive damage of the optic nerve caused by glaucoma. Other pathological mechanisms are also likely to cause retinal ganglion cells (RGC) and Optic nerve damage. All possible causes of RGC apoptosis such as glutamate toxicity, trophic factor disruption, vascular abnormalities,?