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应用ELISA间接法对77例病毒性脑炎患儿入院后脑脊液标本中呼吸进,肠道病毒IgM抗体进行检测,结果共检出致病病毒24例,占全部脑炎的31.37％,其中单纯疱疹病毒8例,占全部脑炎的10.39％;流感病毒6例,占全部脑炎的7.49％;柯萨奇病毒4例,占全部脑炎的5.19%;副流感病毒、腺病毒、EB病毒各2例,各占全部脑炎的2.6％。结果说明单纯疱疹病毒是引起非流行性病毒性脑炎的常见致病病毒,其它病毒致病毒性脑炎有一定流行性,地区性,亦可散在发病。致病率与季节,流行病毒种类有关。提示病毒性脑炎应早期作脑脊液标本中EILISA检查,测定IgM抗休,可早期确定致病病原。
Serum samples of cerebrospinal fluid from 77 children with viral encephalitis were detected by indirect ELISA. 24 cases of pathogenic virus were detected, accounting for 31.37% of all encephalitis, including herpes simplex 8 cases of virus, accounting for 10.39% of all encephalitis; 6 cases of influenza virus, accounting for 7.49% of all encephalitis; Coxsackievirus 4 cases, accounting for 5.19% of all encephalitis; parainfluenza virus, adenovirus, Epstein-Barr virus 2 cases, each accounting for 2.6% of all encephalitis. The result shows that herpes simplex virus is a common causative virus that causes non-epidemic viral encephalitis. Other viral encephalitis viruses have certain epidemic, regional or scattered incidence. The prevalence and the season, the type of epidemic virus. Prompt virus encephalitis should be early EILISA examination of cerebrospinal fluid specimens to determine IgM anti-rest, early identification of pathogenic pathogens.