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C-myc基因是1982年Neel等[1]最早在禽类骨髓细胞瘤病毒29中发现的一种癌基因。心肌重构是心脏功能不全的生物学基础,研究发现,原癌基因c-myc等是细胞增殖调控的早期反应基因,与基因介导的心肌肥厚的病理发生有密切关系,同时它还具有诱导细胞凋...
The C-myc gene was first discovered by Neel et al [1] in 1982 in the myeloblastoma virus 29. Myocardial remodeling is the biological basis of cardiac dysfunction. The study found that proto-oncogene c-myc is an early response gene for cell proliferation regulation and is closely related to the gene-mediated pathology of myocardial hypertrophy. It also induces Cell withering ...