论文部分内容阅读
胆道梗阻和阻塞性黄疸常对肝、肾、心血管和免疫功能产生许多有害的作用,引起细胞连接处的形态破裂,增加血管胆管间的通渗性,破坏血-胆屏障功能.作者进一步研究了经皮肝穿胆道引流(PTBD)减轻上述功能和结构紊乱的效能,发现虽然所有行PTBD后的病人,血胆通透性有所改善,但只有高胆红素血症迅速缓解的病人,才能够恢复选择IgA进入胆道的功能.并认为血清中分泌型IgA水平,是判断肝胆功能的一项很有意义的指标.病例与方法:选择43例手术前行PTBD的病人,其中胆管结石2例,胆道或胰腺肿瘤41例,共取血或肝内胆汁标本78份.将阻塞性黄疸(简称阻黄)病例分成三组:第一组21例,PTBD术前血胆红素高于
Biliary obstructions and obstructive jaundice often have many detrimental effects on the liver, kidney, cardiovascular and immune functions, leading to the rupture of cell junctions, increasing the permeability of blood vessels and bile duct, and destroying the function of blood-gall bladder barrier. Percutaneous transhepatic biliary drainage (PTBD) to reduce the above-mentioned function and structural disorder efficacy and found that although all patients after PTBD improved blood and gallbladder permeability, but only patients with rapid hyperbilirubinemia, Can restore the function of selecting IgA into the biliary tract, and think that the level of secretory IgA in serum is a very meaningful index to judge the function of hepatobiliary.Methods: Forty-three patients with PTBD before operation were selected, including bile duct stone 2 Cases, 41 cases of biliary or pancreatic tumors, a total of 78 cases of blood or intrahepatic bile samples.Objectives of obstructive jaundice (referred to as yellowing) were divided into three groups: the first group of 21 cases, PTBD preoperative serum bilirubin higher than