论文部分内容阅读
目的 观察中药菊花煎灌肠治疗溃疡性结肠炎（Ｕｌｃｅｒａｔｉｖｅ ｃｏｌｉｔｉｓ，ＵＣ） 疗效及对外周血吞噬细胞膜糖蛋白（ＣＤ４４） 和可溶性粘附分子Ｐ 选择素（ＣＤ６２Ｐ） 的影响。 方法 ６４ 例ＵＣ 病人给予中药菊花煎灌肠治疗，并应用流式细胞术，测定ＣＤ４４ 和ＣＤ６２Ｐ的含量。 结果 ＵＣ 病人ＣＤ４４ 和ＣＤ６２Ｐ较正常人明显升高（Ｐ＜ ０ ．０１） ，经中药菊花煎保留灌肠治疗后，ＣＤ４４ 和ＣＤ６２Ｐ含量明显下降，与正常人相比无明显差异（ Ｐ ＞ ０ ．０５） 。 结论 中药菊花煎治疗ＵＣ 疗效肯定，并可降低ＣＤ４４ 和ＣＤ６２Ｐ含量，具有明显的免疫调节作用
Objective To observe the curative effect of traditional Chinese medicine daisy decoction on the treatment of ulcerative colitis (UC) and its effect on peripheral blood phagocytic membrane glycoprotein (CD44) and soluble adhesion molecule P-selectin (CD62P). Methods 64 cases of UC patients given traditional Chinese medicine daisy decoction treatment, and the application of flow cytometry, determination of CD44 and CD62P levels. Results The CD44 and CD62P in patients with UC were significantly higher than those in normal controls (P <0.01). The contents of CD44 and CD62P in patients with UC were significantly lower than those in healthy controls (P> 0.05) ). Conclusion Chinese medicine daisy decoction for the treatment of UC positive, and can reduce the content of CD44 and CD62P, with significant immunomodulatory effects