新生儿颅内出血和维生素K缺乏性婴儿颅内出血,死亡率较高,幸存者常留有脑性瘫痪、智力低下或癫痫等严重的神经系统后遗症。为探索防治小儿脑损伤有效药物提高智能,减少后遗症,我们试用大剂量胞二磷胆硷进行早期预防,治疗新生儿颅内出血16例,维生素K缺乏性婴儿颅内出血7例,均在综合治疗的基础上,病情稳定后,用超出常规量的胞二磷胆硷静脉点滴。开始用 Neonatal intracranial hemorrhage and vitamin K deficiency infants with intracranial hemorrhage, higher mortality, survivors often have cerebral palsy, mental retardation or epilepsy and other serious nervous system sequelae. In order to explore effective prevention and treatment of brain injury in children to improve intelligence, reduce sequelae, we try large doses of citicoline early prevention, treatment of neonatal intracranial hemorrhage in 16 cases, 7 cases of vitamin K-deficient infant intracranial hemorrhage, were in the comprehensive treatment On the basis of stable disease, with more than the conventional amount of intravenous diphosphocholine intravenous drip. Start to use