粟粒性结核病的皮肤表现不常见,结节和脓庖性皮疹已被命名为“播散性粟粒性皮肤结核病”,皮肤病变极少表现为斑丘疹、水疱、出血和大疱,但有报告为无痛性软组织脓肿。粟粒性结核皮肤病变的组织学改变主要为干酪坏死性肉芽肿和阻塞性小动脉炎,并在组织中镜检和培养出结核杆菌。本文报告一例患者在患播散性粟粒性结核病期间,发生双足对称性末梢性坏疽(Symmetrical Peripheral Gang- Miliary tuberculosis has uncommon skin manifestations, nodules and purulent rashes have been named “disseminated miliary cutaneous tuberculosis”, and skin lesions are rarely manifested as maculopapular rash, blisters, hemorrhages and bullous but reported as Painless soft tissue abscess. Histological changes of miliary tuberculosis skin lesions mainly cheese necrotizing granuloma and arteritis, and microscopic examination and culture of Mycobacterium tuberculosis in the tissue. This article reports a case of Symmetrical Peripheral Gang-shaped Symptomatic Gangrene occurring in a patient suffering from disseminated miliary tuberculosis