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目的探讨脑梗死患者传统危险因素与同型半胱氨酸(Hcy)水平的关联。方法选取洛阳市第六人民医院2014年2月至2015年2月收治的脑梗死患者87例作为研究对象,设为观察组;选取同期于我院体检的健康者87例纳入对照组。检测两组患者同型半胱氨酸水平以及传统危险因素比如血压、脂蛋白、血糖、尿酸、甘油、胆固醇等水平,探讨其相关性。结果对照组Hcy水平为(18.32±3.62)μmol/L,明显高于对照组的(12.16±2.74)μmol/L,差异有统计学意义(P<0.05);两组空腹血糖、三酰甘油以及总胆固醇比较差异未见统计学意义(P>0.05);观察组尿酸、脂蛋白以及收缩压明显高于对照组,差异有统计学意义(P<0.05)。结论高Hcy与脑梗死传统危险因素关联度不大,是脑梗死独立危险因素。
Objective To explore the relationship between traditional risk factors and homocysteine (Hcy) level in patients with cerebral infarction. Methods Eighty-seven patients with cerebral infarction who were admitted to the Sixth People’s Hospital of Luoyang from February 2014 to February 2015 were selected as the observation group and 87 healthy subjects were included in the control group. The levels of homocysteine and traditional risk factors such as blood pressure, lipoprotein, blood glucose, uric acid, glycerol and cholesterol in the two groups were detected to explore their correlation. Results The level of Hcy in the control group was (18.32 ± 3.62) μmol / L, which was significantly higher than that in the control group (12.16 ± 2.74) μmol / L, the difference was statistically significant (P <0.05) The difference of total cholesterol was not statistically significant (P> 0.05). The levels of uric acid, lipoprotein and systolic pressure in the observation group were significantly higher than those in the control group (P <0.05). Conclusion High Hcy is not associated with the traditional risk factors of cerebral infarction and is an independent risk factor for cerebral infarction.