AIM:To evaluate the diagnostic accuracy,sensitivity,specificity of contrast-enhanced computed tomographiccolonography in detecting local recurrence of colorectalcancer.METHODS:From January 2000 to December 2004,434 patients after potentially curative resection for in-vasive colorectal cancer were followed up for a periodranging from 20 to 55 mo.Eighty of the four hundredand thirty-four patients showing strong clinical evidencefor recurring colorectal cancer during the last follow-up were enrolled in this study.Each patient underwentcontrast-enhanced computed tomographic colonographyand colonoscopy on the same day.Any lesions,biopsies,identified during the colonoscopic examination,imme-diate complications and the duration of the procedurewere recorded.The results of contrast-enhanced com-puted tomographic colonography were evaluated bycomparing to those of colonoscopy,surgical finding,andclinical follow-up.RESULTS:Contrast-enhanced computed tomographiccolonography had a sensitivity of 100%,a specificity of83% and an overall accuracy of 94% in detecting localrecurrent colorectal cancer.CONCLUSION:Conventional colonoscopy and contrast-enhanced tomographic colonography can complementeach other in detecting local recurrence of colorectalcancer. AIM: To evaluate the diagnostic accuracy, sensitivity, specificity of contrast-enhanced computed tomographiccolonography in detecting local recurrence of colorectal cancer. METHHODS: From January 2000 to December 2004, 4,434 patients after potentially curative resection for in-vasive colorectal cancer were followed up for a periodranging from 20 to 55 mo.Eighty of the four hundred and thirty-four patients showing strong clinical evidence for recurring colorectal cancer during the last follow-up were enrolled in this study. Each patient underwentcontrast-enhanced computed tomographic colonography and colonoscopy on the same day. Any lesions, biopsies, identified during the colonoscopic examination, imme-diate complications and the duration of the procedurewere recorded. The results of contrast-enhanced com-puted tomographic colonography were evaluated by comparing to of of colonoscopy, surgical finding, and clinical follow-up .RESULTS : Contrast-enhanced computed tomographiccolonography had a sensitivity of 1 00%, a specificity of 83% and an overall accuracy of 94% in detecting local recurrent colorectal cancer. CONCLUSION: Conventional colonoscopy and contrast-enhanced tomographic colonography can complementeach other in detecting local recurrence of colorectal cancer.