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采用自身对照方法观察５５例应用枢复宁及胃复安控制化疗所致胃肠道反应的效果。第１周期胃复安与化疗日期同步应用，第２周期枢复宁只在化疗ｄ１应用。结果显示枢复宁在各组方案及含顺铂方案控制急性呕吐有效率分别为９６．４％和８２．８％，明显优于胃复安组（Ｐ＜０．０１）；对于迟发性呕吐有效率在各组化疗方案ｄ２～ｄ５二者无差异（Ｐ＞０．０５），含顺铂方案ｄ２枢复宁优于胃复安（Ｐ＜０．０５），ｄ３～ｄ５无差异（Ｐ＞０．０５）。以上止吐效果与文献中报道一致。胃复安组副反应发生率为３４．５％，枢复宁为９．１％。
The self-control method was used to observe the effect of 55 cases of gastrointestinal reactions caused by chemotherapy with Shenfu Ning and metoclopramide. The first cycle of metoclopramide with the application of chemotherapy date, the second cycle of pivot rather Ning only in the application of chemotherapy d1. The results showed that the effective rate of treatment of acute vomiting in each group and cisplatin regimen was 96.4% and 82.8%, respectively, which was significantly superior to that of metoclopramide (P <0.01) Efficacy of vomiting in each group of chemotherapy regimen d2 ~ d5 no difference between the two (P> 0.05), with cisplatin regimen d2 pivot rehabilitation rather than metoclopramide (P <0.05), d3 ~ d5 no difference P> 0.05). The above antiemetic effects reported in the literature consistent. The incidence of side effects of metoclopram was 34.5% and that of Zu Fu Ning was 9.1%.