类风湿性关节炎(简称RA)以关节病变为主外,全身各器官均可受累,但伴发严重肾损害较为少见,现将我们遇到1例报告如下。患者张某某,男,22岁。因四肢小关节肿痛伴运动受限3年余、夜尿增多1年、双下肢浮肿半月,于1989年9月18日入院。患者于3年前开始有两掌指关节及足跟关节疼痛,进而累及腕、肘、膝及蹠趾关节肿痛,晨僵,活动障碍。曾在当地医院查尿常规发 Rheumatoid arthritis (RA) mainly to joint disease, the body organs may be involved, but with severe renal damage is relatively rare, we now encounter a case report as follows. Zhang Moumou patients, male, 22 years old. Due to limb pain and joint swelling and pain with limited movement more than 3 years, an increase of nocturia for 1 year, double lower extremity edema, on September 18, 1989 admission. Three years ago, patients began to have two metacarpophalangeal and heel joint pains, which in turn affected the wrist, elbow, knee and metatarsophalangeal joint swelling and pain, morning stiffness, and movement disorders. Urine routine check in the local hospital