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观察了各类肝炎患者血清脯氨酸酶（PLD）的活性，以及与谷丙转氨酶（ALT）、谷草转氨酶（AST）之间的关系。结果表明，急性肝炎患者PLD及ALT、AST均显著升高，且PLD与ALT、AST二者水平的变化分别是显著性正相关。动态观察结果显示出PLD恢复正常时间略早于ALT、AST。慢迁肝患者PLD升高的水平与ALT、AST二者变化无明显相关．慢活肝患者PLD与AST显著升高，二者间水平变化呈正相关，而PLD活性与ALT的变化无明显相关。动态观察结果显示，当ALT已恢复正常，而PLD仍持续异常，AST亦明显升高。由此证实，血清PLD活性测定是一项较灵敏、较理想的反映肝细胞损伤程度和肝病慢性化及预后观察方面的客观指标。
The activity of serum proline (PLD), the relationship with ALT and AST in various kinds of hepatitis patients were observed. The results showed that patients with acute hepatitis PLD and ALT, AST were significantly increased, and PLD and ALT, AST both levels were significantly positive correlation. Dynamic observations showed that PLD returned to normal earlier than ALT, AST. The level of PLD in slow-moving liver patients was not significantly correlated with the changes of both ALT and AST. PLD and AST were significantly increased in patients with chronic liver disease, the level of the two was positively correlated, while there was no significant correlation between PLD activity and ALT. Dynamic observation showed that, when ALT has returned to normal, and PLD continued abnormalities, AST was also significantly higher. This confirmed that the determination of serum PLD activity is a more sensitive and ideal to reflect the extent of liver cell damage and chronic liver disease and prognosis of the objective indicators.