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目的 :探讨侵犯前颅窝底恶性肿瘤的诊断和治疗方法。方法 :对 1994～ 1996年收治的 2例少见的头颈部恶性肿瘤进行回顾性分析。结果 :2例均为男性 ,其中头颈部三重癌 1例 ,原发性额窦癌 1例 ,病变广泛侵犯前颅底 ,采取颅面联合进路广泛切除原发性肿瘤。结论 :颅面联合进路是治疗侵犯前颅底骨质头颈恶性肿瘤的最佳方法。多因素的综合作用 ,机体存在多肿瘤易感中心及先证癌发病后接受的放化疗措施和抽烟酗酒等不良生活习惯是头颈多原发癌的重要病因和诱因。合理的综合治疗和严格的首诊、随诊检查可提高诊断率及生存期和生活质量。
Objective: To investigate the diagnosis and treatment of anterior cranial fossa malignant tumor. Methods: Two rare cases of head and neck malignant tumors admitted from 1994 to 1996 were analyzed retrospectively. Results: Two cases were male, including one case of triple head and neck cancer and one case of primary frontal sinus cancer. The lesions were extensively infiltrated the anterior skull base, and the primary tumors were extensively excised by craniofacial combined approach. Conclusion: The combination of craniofacial approach is the best way to treat head and neck malignant tumors of the anterior skull base. The combination of multiple factors, the presence of multiple tumor-prone centers and pre-emptive cancer after the onset of radiotherapy and chemotherapy and smoking habits and other bad habits is an important cause of multiple head and neck cancer causes and incentives. Reasonable comprehensive treatment and strict first visit, follow-up examination can improve the diagnostic rate and survival and quality of life.