地方性克汀病(以下简称地克病)只出现于地方性甲状腺肿流行区,但不同地区的克汀病临床表现确截然不同。1908年Mc Carrison 最先提出神经型和粘液性水肿型,并对前者作了较详尽的描述。继之 Ibbertson 报告了尼泊尔谢尔巴族(Sherpa)人的粘液性水肿型克汀病。现地克病临床类型的划分世界各地已趋一致,即粘液性水肿型、神经型和介于两型间的混合型。这种症状差异这么大的类型是同一疾病的不同表现,还是完全不同的两种疾病,是有过争议的。朱宪彝教授认为:这是一个疾病在症状上的侧重,两者间不象想象的截然分明,两型症状兼而有的混合型到处存在就是很好的说明。因此从病因学上不强调类型的重要,然从另一意义上看,不同类型间也决不单纯只是量上的区别。所以,临床上承认类型区 Local cretinism (hereinafter referred to as grams of disease) only appeared in endemic goiter epidemic areas, but the clinical manifestations of cretinism in different areas is very different. In 1908 Mc Carrison first proposed type of neuropathic and mucinous edema, and made a more detailed description of the former. Then Ibbertson reported on a case of mucocutaneous cretinism in Sherpa, Nepal. Presently, the division of clinical types of g’s disease has become consistent across the world, ie, mucinous edema, neurotic and mixed type between two types. It is controversial that such types of symptoms vary so greatly across different manifestations of the same disease or two completely different diseases. Professor Zhu Xiangyi thinks: This is a symptom of the disease. The difference between the two is not as clear as imagination. Both types of symptoms are mixed everywhere and it is a good illustration. Therefore, from the etiology does not emphasize the importance of type, but in another sense, different types are by no means purely quantitative differences. So, clinically recognized type area