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目的探讨131Ⅰ治疗甲状腺功能亢进性(甲亢)心脏病的近期疗效。方法120例甲亢性心脏病患者均采用单剂量口服131Ⅰ方法治疗,每克甲状腺组织131Ⅰ剂量一般为2.96~4.44 MBq,并结合患者的甲状腺大小、质地、病程长、摄131Ⅰ高峰是否前移、年龄、是否服用过抗甲状腺药物等综合因素适当调整剂量。结果治疗12个月后,甲亢治愈106例占88.33%,其中甲亢性心脏病治愈92例;甲亢好转14例,其中甲亢性心脏病治愈6例。甲亢性心脏病总治愈率81.67%,好转率15.83%,总有效率97.50%。结论131Ⅰ治疗甲亢性心脏病具有疗效好、治愈率高、方法简单、疗程短等优点,可作为病程较长、年龄较大、病情较重的甲亢性心脏病患者的首选治疗方法。
Objective To investigate the short-term curative effect of 131 Ⅰ in the treatment of hyperthyroidism (Hyperthyroidism) heart disease. Methods One hundred and twenty patients with hyperthyroid heart disease were treated with single dose of 131 Ⅰ. The dosage of 131 Ⅰ per gram of thyroid tissue was 2.96-4.44 MBq. Combined with the thyroid size, texture and duration of the thyroid, , Whether taking anti-thyroid drugs and other comprehensive factors appropriate dose adjustment. Results After 12 months of treatment, 106 cases of hyperthyroidism were cured, accounting for 88.33%, of which 92 cases were cured of hyperthyroid heart disease, 14 cases of hyperthyroidism were improved, of which 6 cases were cured of hyperthyroid heart disease. The total cure rate of hyperthyroidism heart disease was 81.67%, the improvement rate was 15.83%, the total effective rate was 97.50%. Conclusion 131 Ⅰ treatment of hyperthyroid heart disease has the advantages of good curative effect, high cure rate, simple method and short course of treatment. It can be used as the preferred treatment for hyperthyroid heart disease patients with longer course, older age and heavier condition.