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双胎动脉灌注顺序颠倒(无心畸形)每100例单 合子多胎妊娠即有1例,双胎中,无心畸形胎儿不能存活,而供血胎儿因心力衰竭和早产致其围产期死亡率超过50％。目前人们对于该病的病理生理所知甚少,仅了解:①单绒毛膜胎盘形成伴两胎儿循环间广泛的动-动脉吻合;②双胎之一动脉灌注顺序颠倒,血流从供血胎儿脐动脉逆流至被灌注胎儿的脐动脉后经其脐静脉回流;③被灌注胎儿无心脏发育或心脏发育很小。其循环颠倒的起因不清,可能系:①胚胎发育不均衡;②不一致性先天性心脏病,其发病率在单合子双胎中增高;③不一致性非整倍体。有
Duplication of fetal arteries permutation was reversed (no cardiac malformations) One case of polycystic pregnancy with 100 cases of congenital polycystic pregnancy did not survive in the twins, whereas the perinatal mortality due to heart failure and preterm birth in the fetuses exceeded 50% . At present, little is known about the pathophysiology of the disease, only to understand: ① the formation of a single choriocarcinoma with extensive arteriovenous anastomosis between two fetal cycles; ② one of the twins reversed the order of arterial perfusion, blood flow from the navel of the fetus Artery countercurrent to be infused fetal umbilical artery after its umbilical vein reflux; ③ was infused fetal heart or little heart development. The reversal of the cause of the cycle is unclear, may be: ① uneven development of embryos; ② inconsistent congenital heart disease, the incidence of unipolar twins increased; ③ inconsistency of aneuploidy. Have