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本文报道妊娠合并原发性血小板减少性紫癜(ITP)22例,其血小板数为(24～76)×10~9/L.妊娠期病情无变化15例,经阴道分娩11例,分娩对致产后出血发生率为31.82%(7/22),新生儿颅内出血发生率为13.64%(3/22).提示:妊娠对部分 ITP 患者病情确有影响,ITP 可导致产后出血,抗血小板抗体可通过胎盘到达胎儿体内,在分娩过程中易引起新生儿颅内出血.在治疗上,应以肾上腺糖皮质激素短期治疗为主,不主张常规剖宫产术,但原则上以适当放宽手术指征为宜.
This article reports 22 cases of pregnancy complicated with thrombocytopenic purpura (ITP), the number of platelets (24 ~ 76) × 10 ~ 9 / L. No change in pregnancy in 15 cases, vaginal delivery in 11 cases, The incidence of postpartum hemorrhage was 31.82% (7/22), neonatal intracranial hemorrhage rate was 13.64% (3/22) .Things: Pregnancy on some patients with ITP indeed have an impact, ITP can lead to postpartum hemorrhage, anti-platelet antibodies Through the placenta to reach the fetus in the childbirth process easily lead to intracranial hemorrhage in neonates .In the treatment, should be based on short-term treatment of glucocorticoid-based, does not advocate conventional cesarean section, but in principle to relax the appropriate surgical indications for should.