太赫兹波光敏效应的初步探索

来源 :中国激光 | 被引量 : 0次 | 上传用户:lhz19700717
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
太赫兹波(THz)是一种介于微波和红外线波之间的电磁波。由于生物体对THz波的独特响应性,太赫兹波在生物医学领域的应用研究特别是其与生物组织的相互作用成为了研究热点。该研究旨在探索太赫兹波能否激发光敏剂产生光敏效应。采用纳焦级宽谱(1~3 THz)的脉冲太赫兹光源对光敏剂(PS)血卟啉单甲醚(HMME)照射30 min,用DPBF作为单态氧的捕获剂检测单态氧产率。采用相同的太赫兹光源照射常规培养的HepG2细胞,光学显微镜下观察细胞形态,MTT法检测细胞活性。PS THz组单态氧产率显著高于单纯太赫兹波组(21.04% vs. 2.39%);PS THz组HepG2细胞形态较对照组略圆,细胞有收缩趋势;细胞活性检测结果显示,太赫兹波照射后HMME孵育的HepG2细胞的活性降低至81.13%(THz组为99.21%)。实验结果表明宽谱1~3 THz纳焦级太赫兹波可激发光敏剂HMME,激发效率约为20%。
其他文献
A 400 nm femtosecond laser was used to ablate the surface of a high-pressure and high-temperature diamond, and subwavelength surface micro structures with a period of 100 nm were achieved. A variety of micro-nano composite surface structures were prepared
本文讨论了一种利用简并四波混频对反射型物体消畸变成像的方法,给出了存在两层位相畸变介质时一个反射点和一个反射型物体的消畸变成像的实验结果.
期刊
Usually, only focused femtosecond (fs) lasers at near-infrared (NIR) range can induce photo-damage to transparent cells, making it difficult to treat large amount of cells by such optical methods for photostimulation. In this study, we clarify the mechani
On the basis of Kolmogorov's theorem, the physical meanings of beams' correlation function on received plane are extended. Approximate formula of channels' across correlation coefficient is deduced from multiple beams through atmosphere. And the scinti
提出了一种简单方便的选支方法,并且计算了光腔的光束参数。
期刊
1977年6月,约用了3周时间访问了美国、英国和西德三国的主要研究所,有机会调查了有关激光研究的实际情况,想概要地作一介绍。
期刊
We present a novel technique to generate an orthogonally polarized optical single sideband (OSSB) generated by a tunable bandpass filter (TBF).When the OSSB passes through the other polarization modulation (PolM) which is polarization dependent, the phase
本文通过对磁光盘系统中偏振光能量传递的计算,研制了实验光路。实验结果表明,理论计算和实验数据一致。
In this research, suitable imaging methods were used for acquiring single compound images of biology samples of chicken pectorales tissue section, tobacco dry leaf, fresh leaf and plant glandular hair, respectively. The adverse effects caused by the high
分析了光纤阵列型点源发生器相对于透镜阵列型点源发生器的优势。针对光纤阵列型点源发生器各光纤出射光束之间存在初始光程差的问题,提出了基于马赫-曾德尔全光纤干涉仪和小数重合法的光程差检测方法。测量各光束间的光程差并将其引入到倾斜波面干涉系统的误差模型中,以消除其对被测件面形偏差解算的影响。结果表明,该检测系统的测量不确定度为0.07λ3(λ3=632.8 nm)。分别使用基于光纤阵列的倾斜波面干涉系