目的　观察药物左室减容术对扩张型心肌病疗效及对远期预后的影响。方法　 38例扩张型心肌病均经超声心动图、X线胸片检查 ,按WHO/ISFC作出诊断 ,并参照NYHA对心功能进行分级 ,按入院先后顺序随机分为治疗组及对照组各 19例 ,两组抗心衰基础治疗相同 ,治疗组在基础治疗同时静脉给予大剂量扩血管、利尿剂、激素强化治疗 ,分别于治疗后第 10d ,2 8d复查相关指标 ,观察疗效及并发症。周期性强化、维持 ,并随访。结果　药物左室减容术在短期内心功能改善、心率减慢、心脏缩小程度及射血分数均优于对照组 (P <0 0 5 )。但并发症 :电解质紊乱、血糖升高高于对照组。治疗组最长随访 2 5年无 1例死亡及心脏重新扩大。结论　药物左室减容术能迅速使扩大的心室缩小 ,从而改善心功能 ,提高生活质量 Objective To observe the effect of drug-induced left ventricular volume reduction on dilated cardiomyopathy and its long-term prognosis. Methods Thirty-eight patients with dilated cardiomyopathy were examined by echocardiography and X-ray and diagnosed according to WHO / ISFC. The cardiac function was graded according to NYHA. Nineteen patients were randomly divided into treatment group and control group The two groups were treated with the same basis of anti-heart failure. The treatment group was treated with intravenous administration of high-dose vasodilator, diuretic, and hormone therapy. The relevant indexes were observed on the 10th and 28th day after treatment respectively, and the curative effect and complications were observed. Periodically strengthen, maintain, and follow-up. Results Left ventricular volume reduction in the short term improved heart function, heart rate, heart rate and ejection fraction were better than the control group (P <0 05). However, complications: electrolyte imbalance, elevated blood sugar than the control group. In the treatment group, the longest follow-up of 25 cases without death and cardiac re-expansion. Conclusions Drug LV volume reduction can rapidly reduce the enlarged ventricle to improve cardiac function and improve quality of life