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目的了解福建省新生儿母传抗体水平,为制定小月龄儿童及育龄期妇女免疫策略提供依据。方法 2013年选取莆田市两家医院住院分娩新生儿,用ELISA法检测麻疹、风疹、腮腺炎和百日咳IgG抗体,分析其母传抗体水平。结果共检测新生儿99人。IgG抗体平均浓度:麻疹779.12mIU/mL、风疹34.05IU/mL、腮腺炎268.96U/mL和百日咳17.07U/mL;Ig G抗体阳性率:麻疹80.8%、风疹85.9%、腮腺炎7.6%和百日咳16.2%。除百日咳抗体阳性率和风疹IgG抗体平均浓度均值存在地区差异外,IgG抗体阳性率及平均抗体浓度在性别、年龄和地区差异均无统计学意义。结论福建省新生儿母传麻疹、腮腺炎IgG抗体水平不高、百日咳IgG抗体水平较低,建议对育龄期妇女加强免疫。
Objective To understand the level of neonatal mother-antibody in Fujian province, and to provide basis for formulating immunization strategies for young children and women of childbearing age. Methods Newborn infants born in two hospitals in Putian in 2013 were tested for measles, rubella, mumps and pertussis IgG by ELISA, and their maternal antibody levels were analyzed. Results A total of 99 newborns were detected. The average IgG antibody levels were: measles 779.12mIU / mL, rubella 34.05IU / mL, mumps 268.96U / mL and pertussis 17.07U / mL; Ig G antibody positive rate: measles 80.8%, rubella 85.9%, mumps 7.6% and pertussis 16.2%. In addition to regional differences in the average prevalence of pertussis antibodies and the average concentration of rubella IgG antibodies, the IgG antibody positive rate and the average antibody concentration in gender, age and regional differences were not statistically significant. Conclusion Neonatal mother-to-child measles and mumps IgG antibody levels are low in newborns in Fujian Province, and pertussis IgG antibody level is low. It is suggested that immunization should be strengthened for women of childbearing age.