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喉癌放射治疗有四个主要合并症:喉水肿、软骨膜炎、软骨坏死、放射性皮肤损害。其中软骨坏死最为严重。作者报导过去15年给T_1和T_2喉癌110例进行放射治疗,其中2例发生软骨膜炎和软骨坏死。例1为女性患者,左声门上鳞状上皮细胞癌侵及左侧会厌、杓会厌皱襞及杓状软骨,伴颈淋结巴转移,属T_3N_1M_0,患者因拒绝手术而作放射治疗,在9 1/2周中接受放射量6,959拉德,7个月后发生呼吸困难而作气管切开。由于进食困难和噁心反应,患者消瘦、脱水。喉部明显水肿,未发现肿瘤复发。死后屍体解剖发现喉软骨坏死、粘膜水肿及溃疡形成,无肿瘤。例2
There are four major complications of laryngeal cancer radiation therapy: laryngeal edema, perichonditis, cartilage necrosis, and radioactive skin damage. Cartilage necrosis is the most serious. The authors reported radiotherapy for 110 cases of T_1 and T_2 laryngeal cancer in the past 15 years, including 2 cases of perichonditis and cartilage necrosis. Case 1 is a female patient with squamous cell carcinoma of the left supraglottal invasion of the left epiglottis, epiglottis folds, and arytenoid cartilage with cervical lymph node metastasis, which is T_3N_1M_0. The patient was treated with radiation for refusal of surgery. /2 Weekly received radiation of 6,959 rads, and dyspnea occurred seven months later for tracheotomy. Due to eating difficulties and nausea, the patient is wasted and dehydrated. Obvious edema in the throat, no recurrence of the tumor. Postmortem autopsies revealed laryngeal cartilage necrosis, mucosal edema, and ulceration without tumors. Example 2