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目的研讨托吡酯与卡马西平治疗脑梗死后继发癫痫医学效果。方法 60例脑梗死继发癫痫患者,随机分为实验组和对比组,各30例。对比组患者采用卡马西平进行治疗,实验组患者给予托吡酯进行治疗,比较两组患者治疗总有效率。结果治疗后,实验组患者中有25例患者完全恢复,3例患者部分恢复,2例患者没有恢复,总有效率达到93%,对比组患者中有18例患者完全恢复,2例患者部分恢复,10例患者没有恢复,总有效率为67%,两组比较,差异具有统计学意义(P<0.05)。结论托吡酯治疗脑梗死后继发癫痫的医学效果较好,能够有效的降低不同类别癫痫的发作频率,可以在临床上大力推广应用。
Objective To investigate the medical effects of topiramate and carbamazepine on epilepsy secondary to cerebral infarction. Methods Sixty cerebral infarction patients with secondary epilepsy were randomly divided into experimental group and control group, with 30 cases in each group. Patients in the control group were treated with carbamazepine, patients in the experimental group were treated with topiramate, and the total effective rate was compared between the two groups. Results After treatment, 25 patients in the experimental group recovered completely, 3 patients partially recovered, 2 patients did not recover, the total effective rate reached 93%, 18 patients in the control group recovered completely and 2 patients recovered partially , 10 patients did not recover, the total effective rate was 67%, the two groups, the difference was statistically significant (P <0.05). Conclusion Topiramate treatment of cerebral infarction secondary epilepsy better medical effect, can effectively reduce the frequency of seizures in different categories of epilepsy, which can be clinically promoted.