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目的观察阿德福韦酯联合复方甘草酸苷治疗慢性乙型肝炎的临床疗效。方法选取2014年1月-2015年1月在医院进行治疗的60例慢性乙型肝炎的患者,随机分为对照组和观察组各30例。观察组给予阿德福韦酯联合复方甘草酸苷治疗;对照组仅给予复方甘草苷治疗。比较2组患者治疗的临床效果。结果 2组患者经过1个疗程的治疗后,观察组总有效率为93.4%高于对照组的73.3%,差异有统计学意义(P<0.05)。且2组患者在治疗后均无不良反应的发生。结论阿德福韦酯联合复方甘草酸苷治疗慢性乙型肝炎临床疗效好,不良反应少,有一定的临床应用价值。
Objective To observe the clinical efficacy of adefovir dipivoxil combined with compound glycyrrhizin in the treatment of chronic hepatitis B patients. Methods Sixty patients with chronic hepatitis B who were treated in the hospital from January 2014 to January 2015 were randomly divided into control group and observation group of 30 cases. The observation group was given adefovir dipivoxil combined with compound glycyrrhizin treatment; the control group only given compound glycyrrhizin treatment. The clinical effects of two groups of patients were compared. Results After 1 course of treatment, the total effective rate in the observation group was 93.4%, which was significantly higher than that in the control group (73.3%), the difference was statistically significant (P <0.05). And two groups of patients after treatment no adverse reactions. Conclusion Adefovir dipivoxil combined with compound glycyrrhizin in the treatment of chronic hepatitis B has good curative effect, few adverse reactions, and has certain clinical value.