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骨肉瘤边界包含着丰富的肿瘤病变的特征信息,对疾病的分类、临床治疗方案设定、疾病预后具有重要意义。分子生物学和基因组学研究的不断深入,为骨肉瘤的分子边界研究提供了理论基础,并且为检测分子边界相关标志物提供了必要的技术手段,一些新的分子标记物也随之被提出并研究。本文就目前相关领域的骨肉瘤分子边界相关标记物进行综述。
Osteosarcoma border contains a wealth of tumor lesions of the characteristics of information on the classification of the disease, clinical treatment program settings, the prognosis of the disease is of great significance. The deepening of molecular biology and genomics research provide the theoretical basis for the study of molecular boundaries of osteosarcoma and provide the necessary technical means for detecting markers related to molecular boundaries. Some new molecular markers are also proposed the study. This review summarizes the related molecular marker of osteosarcoma in related fields.