目的：观察肝细胞生长因子（ＨＧＦ）诱导ＣＣＬ６４ 细胞发生迁移运动及转化生长因子β１（ＴＧＦβ１）对ＨＧＦ诱导的细胞迁移运动的影响。方法：细胞迁移检测。结果：ＨＧＦ不仅具有特异逆转ＴＧＦβ１ 抑制ＣＣＬ６４ 细胞增殖的活性，还具有诱导ＣＣＬ６４ 细胞发生迁移运动的效应。当ＴＧＦβ１ 浓度为５００ ｐｇ／ｍｌ 时，ｒｈＨＧＦ以剂量效应曲线方式诱导细胞迁移，而且低浓度的ＴＧＦβ１（＜１００ ｐｇ／ｍｌ）也可显著增强ｒｈＨＧＦ诱导的ＣＣＬ６４ 细胞迁移。结论：在一定的剂量范围内，ＨＧＦ和ＴＧＦβ１对ＣＣＬ６４ 细胞迁移运动具协同增强作用 Objective: To observe the effects of hepatocyte growth factor (HGF) on the migration of CCL64 cells and the effect of TGF  β1 on HGF-induced cell migration. Methods: Cell migration assay. Results: HGF not only specifically reverses the activity of TGF-β1 inhibiting the proliferation of CCL64 cells, but also induces migration of CCL64 cells. When TGF-β1 concentration of 500 pg / ml, rhHGF dose-response curve induced cell migration, and low concentrations of TGF β1 (<100 pg / ml) can also significantly enhance rhHGF-induced CCL  64 cell migration. Conclusion: In a certain dose range, HGF and TGF β1 CCL64 cell migration exercise synergistic effect