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采用免疫组织化学（ＡＢＣ）法检测河南食管癌高发区新乡市居民食管鳞癌组织中肿瘤抑制基因Ｍａｓｐｉｎ的表达。结果：食管癌组织中Ｍａｓｐｉｎ免疫阳性表达率为１２％（３／２５），免疫阳性反应主要位于癌组织的细胞浆中，其中２例呈局灶型分布，１例呈弥漫型分布。提示：肿瘤抑制基因Ｍａｓｐｉｎ可能在食管癌变过程中起一定的作用。
Immunohistochemistry (ABC) was used to detect the expression of tumor suppressor gene Maspin in esophageal squamous cell carcinoma in Xinxiang, a high incidence area for esophageal cancer in Henan. Results: Maspin positive expression rate in esophageal cancer tissue was 12% (3/25). The immunopositive reaction was mainly located in the cytoplasm of cancer tissue. Two of them were focally distributed, and one case was diffusely distributed. Tip: Maspin, a tumor suppressor gene, may play a role in esophageal carcinogenesis.