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摘要目的研究基于特征性成像参数是否可以预测乳腺导管内原位癌(DCIS)的浸润性。方法纳入活检证实为DCIS的病人65例(其中单侧62例,双侧3例),所有病人行18F-FDG PET成像、扩散加权成像(DWI)或乳腺专用伽马成像(BSGI)检查。PET成像中,测量了SUV_(max)和代表瘤内代谢异质性的累积SUV直方图(CSH)的曲线下面积(AUC)两个参数。肿瘤正常像素比(TNR)和变异系数(COV)作为BSGI成像中异质性的一个参数,ADC最小值(ADC_(min))和ADC最大最小值差异(ADC_(diff))作为DWI中异质性的一个参数。术
Abstract Objective To investigate whether infiltration of breast ductal carcinoma in situ (DCIS) based on characteristic imaging parameters can be predicted. Methods Sixty-five patients (62 unilateral and 3 bilateral) with DCIS were enrolled in this study. All patients underwent 18F-FDG PET imaging, diffusion weighted imaging (DWI) or mammography (BSGI). In PET imaging, two parameters were measured for the area under the curve (AUC) of the SUV max and the cumulative SUV histogram (CSH) representing the intra-tumor metabolic heterogeneity. Tumor normal pixel ratio (TNR) and coefficient of variation (COV) were used as a parameter of heterogeneity in BSGI imaging. The difference between ADC min (ADC min) and ADC max ADC min (ADC diff) A parameter of sex. Surgery