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小鼠肝窦内存在一群特殊的非胸腺来源的 T 淋巴细胞,它们可能在肝脏内而非胸腺内分化成熟。这群细胞表面具有中等密度 T 细胞受体,静止状态下表达 IL-2受体β链,且与自身免疫性疾病、细菌感染、恶性肿瘤的发生、防御等有密切关系。
There is a group of special non-thymus-derived T lymphocytes in the liver sinusoids of mice that may differentiate and mature within the liver rather than the thymus. These cells have medium density T cell receptors on the surface and IL-2 receptor beta chains at rest, which are closely related to the occurrence and defense of autoimmune diseases, bacterial infections and malignant tumors.