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目的:了解基层医疗卫生机构药品不良反应(ADR)情况。方法:运用Excel对2009年1月–2011年12月的132例ADR报告进行分类统计分析,计算ADR例数与ADR发生率。结果:132例ADR的患者中,以50岁以上患者最多;静脉滴注给药引起的ADR124例,占93.94%;抗菌药物导致的ADR最多,共97例,占73.48%;乳酸左氧氟沙星氯化钠注射液的ADR发生率最高,为3.51%;ADR临床表现以皮肤及附件损害最常见,共73例,占55.30%。结论:应进一步加强基层医疗卫生机构ADR的监测,合理使用抗菌药物,注意观察社区老年患者用药过程,促进临床合理用药,避免或减少ADR的发生。
Objective: To understand the adverse drug reactions (ADR) in primary health care institutions. Methods: Using Excel to classify and analyze 132 cases of ADR from January 2009 to December 2011, and calculate the number of ADR cases and the incidence of ADR. Results: Of the 132 patients with ADR, those over 50 years of age had the most patients. ADRs caused by intravenous drip infusion accounted for 93.94%, and ADRs caused by antibacterials were the most, 97 cases (73.48%). ADRs of levofloxacin lactate The incidence of ADR was the highest, accounting for 3.51%. The most common clinical manifestations of ADR were skin and accessory lesions, accounting for 55.30%. Conclusion: The monitoring of ADR in primary medical and health institutions should be further strengthened, antibacterial drugs should be used reasonably, the medication process should be observed in elderly patients in community to promote rational drug use in clinic and avoid or reduce the occurrence of ADR.