低温已用于临床50余年,是目前公认的治疗脑损伤的有效措施,但对于不同低温的脑保护效果,存在争议。Rokkas等认为深低温是治疗脑损伤的最佳方法,而Wass等认为降低2-5℃可获得同样的治疗效果,温度过低反而引起水、钠滞留,细胞肿胀。McDonald等认为28℃以下时不能够提供进一步的脑 Low temperature has been used in clinical for more than 50 years, is currently recognized as effective treatment of brain damage, but for different hypothermia brain protection effect, there is controversy. Rokkas et al. [11] suggested that hypothermia is the best treatment for brain damage. However, Wass et al. Conclude that the same therapeutic effect can be obtained by lowering 2-5 ° C. However, hypothermia causes water and sodium retention and cell swelling. McDonald et al. Concluded that 28 ° C or less did not provide further brains