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选用24只家兔,于右侧下颌骨嚼肌前缘与颏孔之间造成10mm×5mm大小的骨缺损,保留骨膜进行下颌骨骨膜成骨能力的研究。左侧以同样方式去骨但不保留骨膜作对照。动物最长饲养8周,分别用肉眼、X线、组织学和扫描电镜观察。所有实验侧骨缺损完全骨化,对照侧骨缺损未修复。本实验得出如下结论:①下颌骨同膜成骨是一种普遍现象;②成骨以膜内骨生成方式完成,③术后7天即有类骨质产生;④骨膜成骨伴大量血管增生;⑤骨膜成骨细胞生发层以灶性成骨开始。
A total of 24 rabbits were selected. A 10 mm × 5 mm bone defect was created between the frontal edge of the mandibular mandibular muscle on the right side and the mental foramen, and the periosteum was preserved for periosteal osteogenesis. Left in the same way to bone but does not retain the periosteum as a control. Animals were housed for up to 8 weeks, with the naked eye, X-ray, histology and scanning electron microscopy. All experimental lateral bone defects completely ossification, the control side of the defect was not repaired. The experiment concluded that: ① mandibular membrane osteogenesis is a common phenomenon; ② osteogenesis in the form of intramedullary membrane is completed, ③ 7 days after the formation of osteoid; ④ periosteal osteogenesis with a large number of blood vessels Hyperplasia; ⑤ periosteal germinal layer to the beginning of focal osteogenesis.