Sulfamic acid as a green, reusable catalyst for stepwise, tandem & one-pot solvent-free synthesis of

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:mgq
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Sulfamic acid(SA) is a bi-functional, cost-effective and reusable green catalyst for the synthesis of 4-(pyrazol-4-yl)methylenepyrazol-5(4H)-one derivatives by one-pot, three-component condensation of pyrazol-4-carbaxaldehydes, b-ketoesters and phenyl hydrazine(Route-I). In addition to this method,another simple condensation of pyrazol-4-carbaxaldehydes with pyrazolone in the presence of SA under the solvent-free condition in good yield is reported. The merits of these protocols are mild conditions,non-aqueous workup, high yields, easy availability of the catalyst, no chromatographic separation and inexpensive solid acid catalyst. Furthermore, SA could be recycled and reused for five times without losing its catalytic activity. Sulfamic acid (SA) is a bi-functional, cost-effective and reusable green catalyst for the synthesis of 4- (pyrazol-4-yl) methylenepyrazol-5 In addition to this method, another simple condensation of pyrazol-4-carbaxaldehydes with pyrazolone in the presence of SA under the solvent-free condition in good yield is (pyrazol-4-carbaxaldehydes, b- ketoesters and phenyl hydrazine reported. The merits of these protocols are mild conditions, non-aqueous workup, high yields, easy availability of the catalyst, no chromatographic separation and inexpensive solid acid catalyst. Furthermore, SA could be recycled and reused for five times without losing its catalytic activity .
其他文献
干细胞是具有自我增殖和多向分化双重功能的细胞,存在于机体多种组织器官中,如血液、上皮、神经、肌肉、胰腺、肝脏、生殖系统等。随着对干细胞研究的深入,已证明干细胞与老
Benefiting from its bent molecular structure,3,6-pyridazinyl contained tetracationic cyclophane(1) is synthesized by template-directed method with high isolated
A gold-catalyzed intermolecular reaction of ynamides with 3-indolyl azides via the presumable a-imino gold carbenes has been developed, providing an alternative
Direct C—H functionalization of quinoline N-oxides with arylboronic acids is achieved using KMnO_4 as the sole and efficient oxidative system.This method provi
镇海炼化国内首创“硫磺装置加氢催化剂预硫化尾气再脱硫”操作技术,该工艺使硫磺装置开工阶段二氧化硫排放浓度下降7倍以上。在Ⅶ硫磺装置开工过程中,镇海炼化把硫磺装置开
In the radiant section of cracking furnace,the thermal cracking process is highly coupled with turbulent flow,heat transfer and mass transfer.In this paper,a th
A new material for both magnetic coupling and electrocatalytic hydrogen generation based on a copper complex,[(HL)CuCl-CuCl(HL)]HCl 1 is prepared by the reactio
运用程序升温脱附(TPD)实验测定了大马酮、γ-壬内酯、乙基香兰素、乙基麦芽酚和乙酸乙酯五种香气分子在活性炭上的脱附曲线,并根据实验数据计算香气分子在活性炭上的脱附活
2015年8月,“陕西省催化基础与应用重点实验室”获陕西省科技厅(陕科基发[2015]148号)批准建设。该重点实验室依托陕西理工大学,以陕西省化学特色学科为支撑,立足陕南,建立“