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  5. Primary myelofibrosis with concurrent CALR and MPL mutations:A case report

Primary myelofibrosis with concurrent CALR and MPL mutations:A case report

来源 :世界临床病例杂志 | 被引量 : 0次 | 上传用户：feifeijoy
【摘 要】
：
BACKGROUND Primary myelofibrosis(PMF)is a myeloproliferative neoplasm(MPN)characterized by recurrent mutations in the JAK2,CALR,and MPL genes.The CALR and MPL c
【作 者】
：
Feng-Ping Zhou Cheng-Cheng Wan 
【机 构】
：
DepartmentofHematology,AcornmedBiotechnologyCo.
【出 处】
：
世界临床病例杂志
【发表日期】
：
2020年22期
【关键词】
：
Primary myelofibrosis CALR MPL Co-mutation Next-generation sequencing Case repor 
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BACKGROUND Primary myelofibrosis(PMF)is a myeloproliferative neoplasm(MPN)characterized by recurrent mutations in the JAK2,CALR,and MPL genes.The CALR and MPL co-mutation is very rare.To our knowledge,no more than five cases have been reported.Here,we rep
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