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PG05(d1-15甲基PGF_2α甲酯栓剂)是PGF_2α的一种衍生物。我院曾对274例孕妇采用PG05进行药物流产,单纯用药的流产成功率为60.8%,其中完全流产率为44.8%;合用丙酸睾丸酮后,流产成功率达到92.0%,完全流产率亦上升到81.4%,两组之间有非常显著性差异(P<0.001)。妊娠≤8周者合并用药后,流产成功率高达95.2%,完全流产率为87.3%,且流产时间短,副反应少,用药量小。
PG05 (d1-15 methyl PGF_2α methyl ester suppository) is a derivative of PGF_2α. In our hospital, 274 pregnant women were treated with PG05 for medical abortion. The success rate of abortion was 60.8% in simple drug use, and the complete abortion rate was 44.8%. After combined use of testosterone propionate, the successful abortion rate reached 92.0% and the complete abortion rate also rose to 81.4%, there was a very significant difference between the two groups (P <0.001). Pregnancy ≤ 8 weeks were combined with medication, the success rate of abortion as high as 95.2%, the complete abortion rate was 87.3%, and abortion time is short, fewer side effects, the dosage is small.