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目的观察丁溴东莨菪碱联合思密达治疗小儿秋季腹泻的效果。方法对2004年9月～2005年12月间本院的138例病人随机分组进行试验,对照组66例给予常规治疗,治疗组72例在常规治疗的基础上,口服思密达及静滴丁溴东莨菪碱,进行疗效观察。两组均以3天为1个疗程,1个疗程后评定疗效。结果治疗组总有效率(94．4%)明显高于对照组(71．2%)(x~2=10．679,P＜0．01);治疗组痊愈和显效时间均缩短,两组对比有显著性差异(P＜0．01,P＜0．05)。且用药过程中未发现与丁溴东莨菪碱、思密达相关的不良反应。结论丁溴东莨菪碱联合思密达治疗小儿秋季腹泻疗效可靠。
Objective To observe the effect of scopolamine and methidath on children with autumnal diarrhea. Methods A total of 138 patients in our hospital from September 2004 to December 2005 were randomly divided into two groups: control group (66 cases) were given routine treatment, and treatment group (72 cases) were treated with oral metmin and oral Scopolamine, the efficacy of observation. Both groups took 3 days for a course of treatment, after a course of evaluation of curative effect. Results The total effective rate (94.4%) in the treatment group was significantly higher than that in the control group (71.2%) (x ~ 2 = 10.679, P <0.01) There was significant difference between the two groups (P <0.01, P <0.05). No adverse reactions were found to be associated with scopolamine and metamisin during the course of treatment. Conclusion Scopolamine and scimezoate are effective in treating children with autumn diarrhea.