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目的:探讨鼻咽癌组织中的稀土元素含量及其分布特征。方法:以30例鼻咽癌组织为研究对象,应用电感耦合等离子体串联质谱仪(ICP-MS/MS)测定稀土元素含量,并对稀土元素的含量及分布进行分析。结果:鼻咽癌组织中稀土元素含量平均数的标准差数值最小,稀土元素含量轻稀土>中稀土>重稀土,稀土元素含量在鼻咽癌组织中的变化较大,绝对值上Nd、Ce、Pr、Gd等轻稀土元素变化较大;变化程度上Yb、Tb、Ho等重稀土元素变化较大,并存在Eu、Ce的负异常(δEu=0.385 5,δCe=0.523 4)。结论:鼻咽癌组织中稀土元素含量特征符合奇偶分布规律,随着原子序列的增加,含量呈波浪形下降,呈重稀土亏损轻稀土富集型的分布模式,并存在Eu、Ce的负异常。
Objective: To investigate the content of rare earth elements in nasopharyngeal carcinoma and their distribution characteristics. Methods: Thirty cases of nasopharyngeal carcinoma were studied. The content of rare earth elements was determined by inductively coupled plasma mass spectrometry (ICP-MS / MS), and the content and distribution of rare earth elements were analyzed. Results: The average value of rare earth elements in nasopharyngeal carcinoma tissue had the smallest standard deviation, and the contents of rare earth elements> rare earth element> middle rare earth element> heavy rare earth element and rare earth element in nasopharyngeal carcinoma tissues varied greatly. The absolute values of Nd and Ce , Pr, Gd and other light rare earth elements vary greatly. The degree of variation of heavy rare earth elements such as Yb, Tb and Ho varies greatly with the negative anomalies of Eu and Ce (δEu = 0.385 5 and δCe = 0.523 4). CONCLUSIONS: The content of rare earth elements in nasopharyngeal carcinoma (NPC) is in accordance with the distribution of the rare earth elements. The distribution of the REE decreases with the increasing of the atomic sequence, showing the distribution pattern of heavy rare earth depleted LREE enrichment and the negative anomalies of Eu and Ce .