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目的：探讨０．１２５％低浓度布比卡因硬膜外阻滞的分娩镇痛效果及其对母婴的影响。方法：无合并症孕妇６０例，随机分为镇痛组和对照组各３０例。镇痛组于Ｌ２－３行硬膜外穿刺，给０．１２５％布比卡因，首次剂量１２．５ｍｇ～１８．５ｍｇ，必要时追加给药５ｍｌ（６．２５ｍｇ）。结果：０．１２５％布比卡因硬膜外阻滞用于分娩镇痛，第一产程有效率达１００％，第二产程有效率９３．３３％，与对照组比较Ｐ＜０．０１。结论：０．１２５％低浓度布比卡因用于分娩镇痛效果良好，不增加难产率和产后出血率，未见毒性反应及其他副作用。第二产程镇痛不完全可能与追加给药不及时有关。
Objective: To investigate the effect of labor analgesia with low concentration of bupivacaine 0.125% on labor analgesia and its effect on mother and infant. Methods: 60 pregnant women without complications were randomly divided into analgesia group and control group, 30 cases each. The analgesic group was subjected to epidural puncture in line L2-3 to give 0.125% bupivacaine, the first dose of 12.5mg ~ 18.5mg, additional 5ml (6.25mg) if necessary. Results: 0.125% bupivacaine epidural block for labor analgesia, the first stage of labor efficiency was 100%, the second stage of labor efficiency 93.33%, compared with the control group P <0.01. Conclusion: 0.125% low concentration of bupivacaine is effective in analgesia during labor and does not increase the incidence of dystocia and postpartum hemorrhage. No toxic reaction and other side effects are observed. The second stage of labor analgesia may not be completely related with additional administration.