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目的:探讨霜斑样溃疡发病特点。方法:患者经胃镜检查并取活检组织作病理及HP检测(尿素酶试验、Warthin-Starry银染色)。结果:内镜下可见十二指肠粘膜有散在分布约1-2mm白霜斑覆盖者33例,占84.6％。十二指肠粘膜可见一条或多条线形皱襞形成,有散在薄白霜斑付着,粘膜无凹陷者6例,占15.4％。HP检测阳性者30例,阳性率为76.9％。讨论:霜斑样溃疡是一种仅发生于十二指肠特殊类型的消化性溃疡,表现为粘膜呈白色霜斑样改变而无粘膜凹陷性缺损。霜斑样溃疡的病因与十二指肠球部凹陷性溃疡的病因相同,HP感染是引起本病的重要病因之一,胃镜检查为目前检出十二指肠霜斑样溃疡的可靠手段。
Objective: To investigate the incidence of frost-like ulcer. Methods: The patients underwent gastroscopy and biopsy for pathology and HP detection (urease test, Warthin-Starry silver staining). Results: Endoscopic showed duodenal mucosa scattered scattered about 1-2mm frostbite covered 33 cases, accounting for 84.6%. Duodenal mucosa visible one or more linear wrinkles formed, scattered in the thin white cream affixed to the mucosa without depression in 6 cases, accounting for 15.4%. HP test positive in 30 cases, the positive rate was 76.9%. Discussion: Frostbite-like ulcer is a peptic ulcer that occurs only in the special type of duodenum, showing mucosal white frostbite-like changes without mucosal depression defects. The cause of frost-like ulcer is the same as the etiology of duodenal duodenal ulcer. HP infection is one of the important causes of this disease. Gastroscopy is the reliable method to detect duodenal frost-like ulcer.